
Estradiol Vaginal Cream
$39.99
Per month
Each tube is a 3 month supply, billed at $119.97.
Up to 84% of women experience genitourinary symptoms of menopause — vaginal dryness, itching, burning, painful sex, frequent UTIs, yet most go untreated. This localized estradiol cream delivers fast, effective relief.
Note: Pharmaceutical tubes are sealed at the crimp during manufacturing and tube will not have a metal seal.
Includes $0 unlimited doctor access
Delivered to your door for free
HSA/FSA Eligible
Medically reviewed by: Dr. Michelle Montville, Clinical Director & Prescribing Physician
Best for
Learn more about the Estradiol Vaginal Cream
What is it: Estradiol cream is an FDA-approved, plant-based, bio-identical, local hormone treatment for the alleviation of genitourinary symptoms (vaginal dryness, itching, burning, painful sex, frequent UTIs) due to menopause.
Who is it for: Vaginal estradiol cream is recommended for any woman experiencing vaginal symptoms like dryness, burning, itching, frequent UTIs and painful sex.
What am I getting: 1 tube containing 42.5 grams (45 uses) of estradiol cream (0.01%) designed to last three months of use.
How to get it: Prescription required. A menopause-trained doctor will review your medical history to determine if this is the right treatment for you.
A simple, low-dose cream
Multi-symptom relief
See Results in as Little as 12 Weeks!
Safe to use with HRT
O-mazing + Estradiol Vaginal Cream = the perfect combo for improved sexual health
Perimenopause, menopause, and aging mean the possibility of issues like decreased desire, painful sex, dryness, and bladder issues. Our sexual and vaginal health treatments are specially formulated to:
- Relieve dryness, itching, and burning
- Alleviate painful sex
- Decrease frequent UTIs
- Treat bladder issues
- Stimulate natural lubrication
- Enhance arousal and satisfaction
We love 'em on their own, but they're better together. Get $40 off when you buy O-mazing and Estradiol Vaginal Cream together.


Did you know?
80% of women will see improvement in vaginal symptoms within 4-12 weeks of starting treatment
What is Estradiol?
Estradiol is the primary estrogen produced by the body and is considered to be the most powerful. The estradiol in Alloy-prescribed products is molecularly identical to the estradiol your body produces naturally. Our bodies need estrogen for the normal function of multiple organ systems, including our brains, bones, and hearts. As we go through menopause, our estrogen levels dramatically decrease, and this is what causes symptoms. Replenishing your body's natural estrogen in small doses can help you feel your best and stay healthy for longer.
More on Estradiol Vaginal Cream

Do I need Estradiol Vaginal Cream?

Vaginal Itching and Menopause: Causes and Relief

How To Prevent Vaginal Dryness

Understanding Your Libido and How To Improve It
Frequently asked questions
The Alloy Promise
At Alloy Health, we believe every woman deserves thoughtful, evidence-based care, and the information she needs to make confident decisions about her health based on facts, not fear.
Our board-certified physicians follow guidelines from leading medical organizations including ACOG and The Menopause Society and recommend treatments tailored to each patient.























