Estradiol Vaginal Cream Hero
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Plant BasedBioidentical FDA-Approved

Estradiol Vaginal Cream

$39.99

Per month

Each tube is a 3 month supply, billed at $119.97.

Up to 84% of women experience genitourinary symptoms of menopause — vaginal dryness, itching, burning, painful sex, frequent UTIs, yet most go untreated. This localized estradiol cream delivers fast, effective relief.

Note: Pharmaceutical tubes are sealed at the crimp during manufacturing and tube will not have a metal seal.

Includes $0 unlimited doctor access

Delivered to your door for free

HSA/FSA Eligible

Medically reviewed by: Dr. Michelle Montville, Prescribing Physician

A simple, low-dose cream

Multi-symptom relief

See Results in as Little as 12 Weeks!

Safe to use with HRT

Learn more about the Estradiol Vaginal Cream

What is it: Estradiol cream is an FDA-approved, plant-based, bio-identical, local hormone treatment for the alleviation of genitourinary symptoms (vaginal dryness, itching, burning, painful sex, frequent UTIs) due to menopause.

Who is it for: Vaginal estradiol cream is recommended for any woman experiencing vaginal symptoms like dryness, burning, itching, frequent UTIs and painful sex.

What am I getting: 1 tube containing 42.5 grams (45 uses) of estradiol cream (0.01%) designed to last three months of use.

How to get it: Prescription required. A menopause-trained doctor will review your medical history to determine if this is the right treatment for you.

Sexual Health Bundle

Great deal, better sex.

Get $40 off when you buy O-mazing and Estradiol Vaginal Cream together.

Menopause doesn’t mean saying goodbye to your sex life. Estrogen loss can cause dry vaginal skin, painful sex, and a dip in desire.

Estradiol Vaginal Cream restores moisture and improves elasticity.

O-mazing Cream stimulates lubrication and increases blood flow, leading to more fulfilling orgasms.

Together, they make sex feel good again!

Get the Sexual Health Bundle
Sexual Health Bundle with O-mazing
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Did you know?

80% of women will see improvement in vaginal symptoms within 4-12 weeks of starting treatment

Estradiol Molecule

What is Estradiol?

Estradiol is the primary estrogen produced by the body and is considered to be the most powerful. The estradiol in Alloy-prescribed products is molecularly identical to the estradiol your body produces naturally.

Our bodies need estrogen for the normal function of multiple organ systems, including our brains, bones, and hearts. As we go through menopause, our estrogen levels dramatically decrease, and this is what causes symptoms. Replenishing your body's natural estrogen in small doses can help you feel your best and stay healthy for longer.

More on Estradiol Vaginal Cream

Do I need estrogen cream?

Do I need Estradiol Vaginal Cream?

Vaginal Itching During Menopause Relief

Vaginal Itching and Menopause: Causes and Relief

Vaginal Dryness

How To Prevent Vaginal Dryness

Improve Your Libido During Menopause

Understanding Your Libido and How To Improve It

How Alloy Works

We make it easy to connect directly with a menopause-specialized physician.

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The Alloy Promise

At Alloy Health, we believe every woman deserves thoughtful, evidence-based care, and the information she needs to make confident decisions about her health based on facts, not fear.

Our board-certified physicians follow guidelines from leading medical organizations including ACOG and The Menopause Society and recommend treatments tailored to each patient.

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The Alloy Promise